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Epothilone B

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17029
    Epothilone B
    5 Publications Verification

    EPO 906; Patupilone

    		 Microtubule/Tubulin Fungal Apoptosis Antibiotic Bacterial Infection Cancer
    Epothilone B is a microtubule stabilizer with a Ki of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation.
    <em>Epothilone</em> <em>B</em>
  • HY-10222
    Ixabepilone
    3 Publications Verification

    BMS-247550; Aza-Epothilone B

    		 Microtubule/Tubulin Apoptosis Bacterial Cancer
    Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis.
    Ixabepilone
  • HY-107020
    BMS 310705

    21-AminoEpothilone B

    		 Apoptosis Cancer
    BMS 310705 (21-Aminoepothilone B) is an analog of Epothilone B (HY-17029), targeting to malignancies such as ovarian, renal, bladder, and lung carcinoma. BMS 310705 induces significant apoptosis via mitochondrial-mediated pathway .
    BMS 310705

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